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WebFeb 7, 2024 · Electronic address: [email protected]. PMID: 30639240 PMCID: PMC6858279 DOI: 10.1016/j.molcel.2024.11.021 Abstract CRISPR-Cas12a (Cpf1) is an RNA-guided DNA-cutting nuclease that has been repurposed for genome editing. Upon target DNA binding, Cas12a cleaves both the target DNA in cis and non-target single … WebOct 27, 2024 · Electronic address: [email protected]. PMID: 36306733 DOI: 10.1016/j.cell.2024.09.026 Abstract The target DNA specificity of the CRISPR-associated genome editor nuclease Cas9 is determined by complementarity to a 20-nucleotide segment in its guide RNA. However, Cas9 can bind and cleave partially complementary off-target … WebApr 18, 2024 · “Voormalig politiek assistent van D66, Marleen Weener: "Ik ben 10 jaar lang lid geweest en heb eigenlijk nooit mezelf kunnen zijn. Ik heb bijvoorbeeld nooit iemand … god eater id fe2cm