WebMar 17, 2016 · You could protect the primary amine, for example with phthaloyl, then protect the secondary amine, and then remove the phthaloyl group (see Greene's Protective Groups). However, it... WebThe research group in Strasbourg on liquid crystalline materials are pioneers in this Greene’s Protective Groups in Organic Synthesis, field. The authors have structured the review well by focusing 4th ed. By Peter …
Greene
WebGreene, Theodora W., 1931-Protective groups in organic synthesis. II. Title. QD262.G665 2006 547.2–dc22 2006016601 Printed in the United States of America 10 9 8 7 6 5 4 3 2 … Web1,3-Dioxanes and 1,3-dioxolanes can easily be prepared from carbonyl compounds with 1,3-propanediol or 1,2-ethanediol in the presence of a Brönsted or a Lewis acid catalyst. 1,3-Diols give more stable compounds. A standard procedure for protection employs toluenesulfonic acid as catalyst in refluxing toluene, which allows the continuous ... lauseenvastike
13.10: Protecting Groups in Organic Synthesis - Chemistry …
Web18 rows · A protective group (also referred to as "protecting group") is a reversably formed ... WebA protecting group or protective group is introduced into a molecule by chemical modification of a functional group to obtain chemoselectivity in a subsequent chemical reaction. It plays an important role in multistep organic synthesis. [1] WebAnother interesting development is the design and use of protective groups with a built-in 'safety-catch', which can be 'released' by a specific chemical reaction, so that an otherwise stable bond is made labile at the appropriate moment thereby allowing the protective group to be removed under very 2 mild conditions. lauseenvastike englanti